The History of Cialis

Cialis (tadalafil) treats erectile dysfunction – a condition where men are unable to achieve an erection during sexual activity. For obvious reasons, this is very frustrating for men who have this condition, which is why they seek medications such as tadalafil. Understanding the history of this drug helps in comprehending its intended purpose.

The Development of Cialis

Cialis was officially approved by the FDA on November 21, 2003. This medication became a prescription drug to treat erectile dysfunction in a rather interesting way.

It all began when in 1994, a scientist for Pfizer discovered that the substance Sildenafil Citrate gave patients with heart-related problems easier erections during clinical studies.

This was rather rare, but he decided to investigate this matter a little further. It was discovered that this drug (Sildenafil Citrate) was lowering the levels of PDE5 within males which then enhanced levels of cGMP – the substance that controls the dilation and contraction of the blood vessels that carry blood to and from the penis.

Pfizer, being an immense drug company provider, began conducting trials for tadalafil hoping to treat heart conditions. Instead, there were very unusual symptoms reported from the men being tested. Male volunteers said they got erections when on this drug.

The accidental discovery of another drug (Sildenafil) paved a way to Cialis or tadalafil. It brought forward a solution to men suffering from erectile dysfunction. Making the connection between Sildenafil (a PDE5 enzyme inhibitor) and IC351 (tadalafil) brought scientists a completely different perspective on this compound.

Because chemical compound IC351 wasn’t being tested for erectile dysfunction at the time, the scientists at ICOS Corp began researching their drug. Giving it a closer look, they found the secret ingredient to treat erectile dysfunction. In 1998, ICOS partnered with Eli Lilly Company and continued developing IC315 until in 2002, they announced the brand name – Cialis.

It was discovered that Cialis would work up to 36 hours giving men pleasurable sexual experiences. It facilitated the process of getting an erection and quickly rose in popularity. Not only did the FDA approve this drug for erectile dysfunction but also for treating Benign Prostatic Hyperplasia (BPH).

The discovery of tadalafil was an accident and it has changed many lives since then. While there were other treatments such as Viagra that treated this erectile dysfunction, Cialis resulted in being a great alternative to this drug. A great step forward in treating this condition for males, many men experience longer and harder erections during sexual intercourse.

Inactive Ingredients

So, what exactly is in Cialis that helps men achieve an erection during sexual activity? After much testing and conducted research, the developers of this drug included 11 inactive ingredients that give this small pill its power. While users don’t have to understand exactly what each ingredient does, they should know that Cialis is safe to use for the majority of men.

We should clarify that this drug is safe to use for healthy adults or patients who have gotten this medication approved by their doctor. There are exceptions to who can use this based on health history, current conditions, or if the patient is on any other medications.

The best advice we can give to ensure you are practicing a safe intake of this drug is to speak with your medical provider prior to use. While you need a prescription for Cialis, you can use a legitimate online pharmacy for more convenience. Just be sure to verify the legitimacy of the online pharmacy that you choose, as there are online providers who sell artificial or poorly made medication.

In addition, the formula of Cialis is C22H19N3O4 and it has a molecular weight of 389.41. This drug comes in the form of a yellow, almond shape tablet and is consumed orally. Every table contains the following inactive ingredients:

  • Titanium dioxide
  • Iron Oxide
  • Croscarmellose sodium
  • Sodium lauryl sulfate
  • Hydroxypropyl cellulose
  • Hypromellose
  • Lactose Monohydrate
  • Microcrystalline cellulose
  • Talc
  • Triacetin
  • Magnesium stearate

Cialis Dosing Information

Dosages can be obtained in tablets of 2.5, 5, 10, or 15 milligrams. They should be taken with caution and as prescribed. For instance, most patients starting off will be instructed to take 2.5 or 5 milligrams orally every day before sexual intercourse. Depending on how the body reacts, your doctor may suggest an increase or decrease in your dose.

For men who plan on being sexually active every day, an initial dose of 2.5 mg is recommended at the same time of the day (doesn’t matter the time of sexual activity). Again, depending on the efficacy and tolerability of this drug, users can adjust intake as needed. For any concerns, be sure to speak with your medical provider.

Side Effects

If you experience any allergic reactions such as difficulty breathing, hives, or swelling get emergency help immediately. During sexual intercourse, if you notice chest pains, dizziness, or nausea you need to get to a doctor as soon as possible as you may be having an intense side effect to this drug.

While very little symptoms have been reported regarding Cialis, common side effects include:

  • Muscle pain (back, arms, legs)
  • Headache
  • Tingly feelings (feeling flushed)
  • Stomach ache
  • Stuffy nose

There are also other conditions that may prevent you from being suited to take this drug. For healthy males that are not currently under any medications, there is no reason Cialis won’t work for them. However, if you suffer from a heart condition or have had a stroke within the past 6 months this is not for you.

Cialis was a great invention and without a doubt one of the best treatments for erectile dysfunction. Always keep in mind that this along with other medicines needs to be kept out of reach of children and never shared with other adults.

If you’re wondering if Cialis is for you, speak with your medical provider. Men who suffer from chest pain or heart-related problems are normally advised to say away from Cialis as it can make their conditions worse. If this happens to be the case, remember that there are alternatives to this drug.